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Viagra Pills: Viagra (Viagra) – instructions for use, composition, drug analogs, dosages, side effects

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Viagra Pills: Viagra (Viagra) - instructions for use, composition, drug analogs, dosages, side effects

Viagra® (Viagra®) – instructions for use, composition, drug analogues, dosages, side effects

Description of the drug how much does viagra cost Viagra® (Viagra®): composition and instructions for use, contraindications, prices in the Encyclopedia of drugs radar

To diagnose erectile dysfunction, determine their possible causes, and select an adequate treatment, it is necessary to gather a full medical history and conduct a thorough physical examination. Erectile dysfunction treatment should be used with caution in patients with anatomical deformation of the penis (angulation, cavernous fibrosis, Peyronie’s disease) or risk factors for the development of priapism (SKA, multiple myeloma, leukemia) (see Precautions).

During postmarketing studies, cases of prolonged erection and priapism have been reported. If an erection persists for more than 4 hours, you should immediately seek medical attention. If priapism therapy was not carried out immediately, it can cause damage to the tissues of the penis and irreversible loss of potency.

Drugs for treating erectile dysfunction should not be given to men for whom sexual activity is undesirable.

Sexual activity poses a certain risk in the presence of heart disease, therefore, before starting any therapy for erectile dysfunction, the doctor should refer the patient to an STS examination. Sexual activity is undesirable in patients with heart failure, unstable angina, suffered myocardial infarction viagra and alcohol or stroke, life threatening arrhythmias, hypertension (BP> 170/100 mm Hg) or hypotension (BP) in the last 6 months. <90/50 мм рт.ст.). Прием силденафила у таких пациентов противопоказан (см. «Противопоказания»). В клинических исследованиях показано отсутствие различий в частоте развития инфаркта миокарда (1,1 на 100 человек в год) или частоте смертности от сердечно-сосудистых заболеваний (0,3 на 100 человек в год) у пациентов, получавших препарат Виагра®, по сравнению с пациентами, получавшими плацебо.

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Cardiovascular complications

The post-marketing use of sildenafil for the treatment of erectile dysfunction reported adverse events such as severe cardiovascular complications (including myocardial infarction, unstable angina, sudden cardiac death, ventricular arrhythmia, hemorrhagic stroke, transient ischemic stroke, I, I, I haven’t put a template, transient ischemic heart attack, I have an unpleasant heart attack, ventricular arrhythmia, hemorrhagic stroke, transient ischemic stroke, and I have an unpleasant heart attack, sudden heart death, ventricular arrhythmia, hemorrhagic stroke, transient ischemic stroke, transient ischemic attack, and I have already applied a cardiac abnormality. ), which had a temporary connection with over the counter viagra substitute the use of sildenafil. Most of these patients, but not all of them, had risk factors for cardiovascular complications. Many of these adverse events were observed shortly after sexual activity, and some of them were observed after taking sildenafil without subsequent sexual activity. It is not possible to establish the existence of a direct connection between the observed adverse events and the specified or other factors.

Viagra Pills: Viagra (Viagra) - instructions for use, composition, drug analogs, dosages, side effects

Hypotension

Sildenafil has a systemic vasodilating effect, leading to a transient decrease in blood pressure generic viagra online, which is not a clinically significant event and does not lead to any consequences in most patients. However, before prescribing Viagra®, the doctor should carefully evaluate the risk of possible undesirable manifestations of the vasodilating action in patients with relevant diseases, especially against the background of sexual activity. Increased susceptibility to vasodilators is observed in patients with obstruction of the left ventricular output tract (aortic stenosis, GOKMP), as well as rarely occurring syndrome of multiple systemic atrophy, manifested by severe dysregulation of blood pressure by the autonomic nervous system.

Since the combined use of sildenafil and α-blockers can lead to symptomatic hypotension in individual sensitive patients, Viagra® should be prescribed with caution to patients taking α-blockers (see “Interaction”). To minimize the risk of postural hypotension viagra samples in patients taking α-adrenergic blockers, taking Viagra® should be started only after stabilization of hemodynamic parameters in these patients is achieved. It should also be considered the feasibility of reducing the initial dose of the drug Viagra® (see “Dosage and administration”). The physician should inform the patient about what action should be taken in case of symptoms of postural hypotension.

Visual impairment

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In rare cases, during post-registration use of all PDE-5 inhibitors, incl. Sildenafil, reported NPINZN – a rare disease and the reason for the reduction or loss of vision. Most of these patients had risk factors, in particular a decrease in the ratio of excavation diameters and optic nerve head (congestive disc), over 50 years of age, diabetes, hypertension, coronary heart disease, hyperlipidemia and smoking. In an observational study, it was evaluated whether the recent use of drugs of the class of PDE-5 inhibitors is related to the acute onset of NPINSN. The results indicate an approximately 2-fold increase in the risk of NPINZN within 5T1 / 2 after the use of a PDE-5 inhibitor. According to published literature data, the annual incidence of NPINSN is 2.5–11.8 cases per 100,000 men ge; 50 years in the viagra prank general population. Patients should be advised to discontinue sildenafil therapy in the event of a sudden loss of vision and consult a physician immediately.

Persons who have already had a case of an NPINZN have an increased risk of a recurrence of an NPINZN. Therefore, the physician should discuss this risk with such patients, as well as the potential chance of adverse effects of PDE-5 inhibitors. PDE-5 inhibitors, incl. Sildenafil, in such patients should be used with caution and only in situations where the expected benefit outweighs the risk viagra generic name. In patients with episodes of development of NPINZN with loss of vision in one eye, sildenafil is contraindicated (see “Contraindications”).

A small number of patients with hereditary retinitis pigmentosa have genetically determined dysfunctions of the retinal PDE. Information about the safety of Viagra® in patients with retinitis pigmentosa is absent, so sildenafil should not be used in these patients (see “Contraindications canadian viagra”).

Viagra Pills: Viagra (Viagra) - instructions for use, composition, drug analogs, dosages, side effects

Hearing loss

In some post-marketing and clinical studies reported cases of sudden deterioration or loss of hearing associated with the use of all PDE-5 inhibitors, including sildenafil. Most of these patients had risk factors for sudden deterioration or hearing loss. A causal relationship between the use of PDE-5 inhibitors and a sudden deterioration in hearing or hearing loss has not been established. In case of sudden hearing loss or hearing loss with sildenafil intake, you should immediately consult with your doctor.

Bleeding

Sildenafil enhances the antiplatelet effect of sodium nitroprusside, a nitric oxide donator, on human platelets in vitro. There are no data on the safety of using sildenafil in patients with a tendency to bleeding or exacerbation of gastric ulcer and duodenal ulcer, therefore Viagra® should be used with caution in these patients (see With caution).

The frequency of nasal bleeding in patients with pulmonary hypertension associated with diffuse connective tissue diseases was higher (sildenafil – 12.9%, placebo – 0%) than in patients with primary pulmonary arterial hypertension (sildenafil – 3%, placebo – 2, four%). In patients receiving sildenafil in combination with a vitamin K antagonist, the frequency of nosebleeds was higher (8.8%) than in patients not taking a vitamin K antagonist (1.7%).

Use in conjunction with other treatments for erectile dysfunction.

The safety and efficacy of Viagra® together with other PDE-5 inhibitors or other drugs for the treatment of pulmonary arterial hypertension how to get viagra containing sildenafil (for example, Revacio®), or other means for generic viagra cost treating erectile dysfunction have not been studied, therefore the use of such combinations is not recommended (see “Contraindications”).

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Influence on the ability to drive and mechanisms. Against the background of sildenafil intake, there was no negative effect on the ability to drive a car or other technical means. However, since the administration of sildenafil may develop dizziness, lower blood pressure, the development of chromatopsia, blurred vision, etc. side effects, caution should be exercised when driving and engaging in other potentially hazardous activities that require increased concentration and psychomotor reactions. You should also be attentive to the individual action of the drug in these situations, especially at the beginning of treatment and when changing the dosage regimen.